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8th Edition – June 18, 2012

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BioHealth Innovation, Inc. Names Richard Bendis President & Chief Executive Officer

 

Rich Bendis

BioHealth Innovation, Inc. (BHI), a regional private-public partnership focusing on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in Central Maryland, announced today that its Board of Directors has named former Interim CEO Richard Bendis as the organization’s first President & Chief Executive Officer.

Scott Carmer, BioHealth Innovation, Inc. Chairman of the Board and Executive Vice President of Commercial Operations at MedImmune, said, "The Board unanimously supported the appointment of Rich Bendis as BHI’s President and CEO. As the interim CEO, Rich has been instrumental in establishing BHI, securing significant private and public sector support and funding, and developing and executing on long- and short-term strategic goals. Rich possesses unique knowledge and experience that will allow him to continue BHI’s tremendous momentum to accelerate biohealth commercialization opportunities for Central Maryland."

 

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MedImmune CEO Peter Greenleaf, Human Genome Sciences CEO Tom Watkins, Montgomery County, Maryland Executive Isiah Leggett Come Together

 

bio-internation-convention

The Montgomery County Department of Economic Development will host a press event highlighting the nation’s first local biotech investment incentive program, initiated by Montgomery County government, the role local biotech entrepreneurs, many from County-based federal labs like NIH and FDA, play in the success of the sector and a new, regional, industry-sector led intermediary created to bolster technology transfer into commercial success during the BIO International Convention in Boston.

WHEN: Tuesday, June 19, 2012 from 3:00-4:30pm EDT.

WHERE: The Boston Convention and Exhibition Center, MA – Maryland Pavilion

WHAT: Press event featuring: MedImmune CEO Peter Greenleaf discussing the growth and success of that company in Montgomery County and that company’s leading role in supporting the newly formed BioHealth Innovation, Inc. (BHI) – an industry-lead biotech intermediary; Human Genome Sciences CEO Tom Watkins discussing the growth and success of that company in Montgomery County and the supportive local government and innovative initiatives and policies that support the sector; Montgomery County Executive Isiah Leggett discussing the success of the County’s local biotech investment incentive program and BHI Board Chair Scott Carmer, Executive Vice President, Commercial Operations for MedImmune and BHI CEO Rich Bendis discussing the early initiatives and successes of that new regional entity in bolstering the success of the region’s biotech sector.

 

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Human Genome sets deadline for buyout offers – CBS News

 

human-genome-sciences

Biotech drugmaker Human Genome Sciences Inc. is giving all bidders until July 16 to submit their final buyout offers and appealed to GlaxoSmithKline PLC to participate even though its prior bid was rejected.

The Rockville, Md.-based company said Friday that it is committed to exploring its strategic options.

Human Genome rejected the British pharmaceutical giant’s $13 per share offer last month, saying it was inadequate. At that time the company also adopted a "poison pill" shareholder rights plan in order to ward off any unsolicited takeover bids.

 

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Maryland entrepreneurs urge culture change – MDBIZNews

 

Serial entrepreneur panel small

A panel of entrepreneurs told the Maryland Economic Development Commission on Tuesday that Maryland needs to commercialize more discoveries made in academic and government labs and improve the entrepreneurial culture if the state hopes to compete with traditional hubs of innovation.

“You ain’t gonna replicate Silicon Valley and Boston in many places around the world. What Maryland has is unrivaled research assets that, basically, most states cannot compete with,” said Rich Bendis, interim CEO of BioHealth Innovation Inc. “The difference is, we’re talking about culture. It’s the entrepreneurial culture that’s different in those other cities.”

Bendis said Maryland’s stature is improving in the eyes of entrepreneurs and those tasked with supporting startups.

 

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U. of Maryland to Count Patents and Commercialization in Tenure Reviews – Administration – The Chronicle of Higher Education

 

University System of Maryland

The University System of Maryland is about to adopt a new policy to formally give credit in tenure and promotion decisions for faculty work that leads to patents and other intellectual property applied in technology transfer.

The new policy, slated for final Board of Regents approval on June 23, is part of the system’s broader push to promote the commercialization of academic research.

Maryland institutions receive a lot of research money but have been "very run of the mill" when it comes to transforming that research into useful products and services, said William E. (Brit) Kirwan, chancellor of the system, in an interview on Wednesday. "The culture of commercializing intellectual property just hasn’t existed in Maryland."

 

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MdBio Foundation to Launch National Gaming Initiative to Improve U.S. STEM Education – MarketWatch

 

Md bio enterprise

In response to the declining state of science education in America, MdBio Foundation, Inc. today announced it will provide science teachers and students nationwide with an innovative and immersive educational video game platform free of charge beginning in 2013. The online platform, called MdBioSphere(TM), seeks to advance student comprehension in science, technology, engineering and math (STEM) and revitalize student interest in science-related careers through the use of innovative gaming technology. The serious game is being developed by Hunt Valley, Md.-based BreakAway, Ltd., and will be previewed at the BIO International Convention (June 18-21, 2012, Booth 0753 in the Maryland Pavilion) in Boston.

"The Foundation believes that creating a globally-competitive U.S. workforce begins in the classroom," said J.J. Finkelstein, chairman of the MdBio Foundation. "The MdBioSphere platform, which will be the first serious game platform to be mapped to the new U.S. science education standards, can be a breakthrough application that helps inspire the next generation of scientists that America needs if we are to compete in the 21st century. The MdBioSphere platform merges the captivating elements of online gaming with educationally-driven STEM curricula to deliver an exciting classroom experience that enriches both students and teachers."

 

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InvestMaryland preps to dole out $56M to venture capital firms – Washington Business Journal

 

Greenleaf Peter05-cx250

Maryland officials are preparing to dole out the first investments of the $84 million InvestMaryland program this summer, but they must first whittle down a list of 37 venture capital firm applicants to about half a dozen.

The funding will essentially make the state a limited partner in five to eight VC firms, which will be tasked with routing the funds back into Maryland tech and biotech startups in a traditional VC role. A list of recommended firms is due to be released later this month.

 

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NCATS Funding Opportunities for Industry Partnerships to Develop Repurposed Drugs

 

NCATS

NCATS at the NIH has released two RFAs on Discovering New Therapeutic Uses for Existing Molecules (UH2/UH3).  Applications are due on December 17, 2012.  

The National Center for Advancing Translational Sciences (NCATS) seeks to develop a therapeutics discovery pilot program that will explore new therapeutic uses for proprietary drug candidates (Agents) across a broad range of human diseases. This innovative program will match Agents and associated data from pharmaceutical company partners with the best ideas for new therapeutic uses from the biomedical research community.

 

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Loh Launches UMD Innovation Outreach to Taiwan, Korea :: University Communications Newsdesk, University of Maryland

 

University of Maryland President Wallace Loh is extending his Asia strategy with an innovation tour of Taiwan and South Korea. IUMD President Loh Asian his third trip to the region, Loh is laying the groundwork for new research and educational partnerships through sessions with high-level government, industry and academic officials.

Follow Loh’s live blog from Asia: http://ter.ps/vt

"Science and education transcend borders," Loh says. "A premier innovation and entrepreneurship university needs to operate in a global context today if it is to serve the state and the nation. By building new research collaborations, bringing Asian companies to our international incubator, and fostering intercontinental student exchanges, we keep Maryland plugged into the economic and intellectual currents."

 

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HHS names Sivak new chief technology officer – Washington Business Journal

 

DHHS

The Department of Health and Human Services has named Brian Sivak as the department’s next chief technology officer, according to Federal News Radio.

Sivak, currently chief innovation officer for Maryland Governor Martin O’Malley and the former chief technology officer for the District of Columbia, will join HHS next month and also serve as tech entrepreneur-in-residence.

 

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University of Maryland continues cyber push with Northrop partnership – Washington Business Journal

 

northrop-gruman

Thanks in part to its proximity to the federal government, the University of Maryland has shaped itself into one of the few institutions that specialize in cybersecurity — contributing its own resources, while also relying on financial contributions and expertise from the Washington area’s biggest government contractors.

The university’s latest announcement came Monday from Falls Church-based Northrop Grumman Corp. , which will provide UMd. a $1.1 million grant to create the nation’s first cybersecurity honors program for undergraduates, dubbed the Advanced Cybersecurity Experience for Students. The program will kick off this fall, and Northrop will support it for an additional two years.

 

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Shady Grove Office Center lands Tech Council of Maryland headquarters – Washington Business Journal

 

Techcouncilmd

The Tech Council of Maryland has moved into its new headquarters in the Shady Grove Office Center, Citybizlist.com reports.

The new location, at 9210 Corporate Blvd. in Rockville, is a short distance from the Tech Council’s previous offices on Key West Avenue. The group has more than 400 biotechnology and technology members.

 

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PhaseBio Pharmaceuticals Closes $48.4M Series B -peHUB

 

PhaseBio

PhaseBio Pharmaceuticals Inc., a clinical-stage biotechnology company developing drugs to treat diabetes, metabolic disease and cardiovascular disease, has closed its Series B round with a total of $48.4 million, the company announced. The round closed after a third tranche.

PhaseBio is backed by New Enterprise Associates, Astellas Venture Management, Johnson & Johnson Development Corp., Hatteras Venture Partners and Fletcher Spaght Ventures.

 

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Lynn-Ann Gries: With Organized Angels on Their Side, Can Start-ups Really Start Up Anywhere in the Country?

 

angel-capital-assoc

Raise your hand if you realized the Midwest has become a hotbed of angel group activity — and a well-respected resource of nationally respected investment knowledge. This spring, Tony Shipley represented the Angel Capital Association, a professional alliance of angel groups in the United States and Canada, in front of a Congressional subcommittee discussing equity finance as a catalyst for small business growth. The software entrepreneur, who founded the Cincinnati-based angel network, Queen City Angels= in 2000, testified about the financial and intellectual capital angel investors provide, while making suggestions on how Congress can use legislation and public policy to bolster the entrepreneurial ecosystem.

Shipley’s presence at this meeting illustrates the growing national attention given to Midwest angels, who are making the region a hub for innovation. According to the 2011 HALO Report, 79 percent of angel group investments occurred outside of traditional funding mecca California. Of these investments, the Great Lakes region received the biggest proportion of them — 15.9 percent, a percentage greater than the shares of innovation-rich regions such as New England and the Southeast.

 

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Maryland’s 18 Most Promising Incubator Companies – Citybizlist Baltimore

 

MD Incubator

The 12th Annual Maryland Incubator Company of the Year Awards, supported by the Maryland Department of Business and Economic Development (DBED), the Maryland Technology Development Corporation (TEDCO), McGladrey, Inc. and Saul Ewing, is coming up.

The ceremony will recognize the achievement and potential among 18 current and graduate companies within Maryland’s incubator network. Chris Brandenburg from Millennial Media, who received the 2008 information technology Incubator Company of the Year award, will be the keynote speaker. The event will also feature technology demonstrations by the finalist companies.

 

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UMBC Incubator Gets New Cyber Security Firms

 

Bwtech-UMBC

The incubator at University of Maryland, Baltimore County has gotten an influx of new tenants, the majority of whom are responding to the increased demand for cyber security. 

bwtech@UMBC Research and Technology Park currently hosts 86 incubator and early-stage tenants and 14 affiliated companies and organizations, according to Gregory Simmons, the park’s vice president for institutional advancement.

Of the tenants, nearly 20 have joined the park in the past 18 months alone. They include Fearless Solutions, Rogue Technology, AIS (Assured Information Security) Inc., all of which are in the cyber security field.  Simmons says that most of the new tenants are also in that field, often in the area of securing data and networks, in medical, defense and financial services, among others.

 

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Immunomic Therapeutics’ CEO, Dr. William G. Hearl, to Present at 2012 BIO International in June

 

immunomic-therapeutics

Immunomic Therapeutics, Inc., ("ITI") a privately-held biotechnology company with laboratories in Rockville, MD, announced that it has been accepted to present at the Business Forum during the 2012 Bio International Convention. ITI’s CEO, Bill Hearl, will present progress in internal development of LAMP-vax™ vaccines as well as opportunities for co-development.

JRC-LAMP-vax vaccine incorporates Immunomic Therapeutics’ proprietary LAMP Technology™. LAMP (Lysosomal Associated Membrane Protein) is a normal and important component of the immune system that is present in the lysosome of all mammals. Incorporating LAMP Technology into vaccine design enables direct presentation of

 

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Immunomic Therapeutics Receives IND Authorization from FDA for Phase I Study of Japanese Red Cedar LAMP-vax Vaccine

 

immunomic-therapeutics

Immunomic Therapeutics, Inc., ("ITI," Lancaster, PA) a privately-held biotechnology company with laboratories in Rockville, MD, announced that the U.S. Food and Drug Administration (FDA) has completed its review of the Investigational New Drug Application ("IND") filed for the allergy immunotherapy, JRC- LAMP-vax™.  On April 12th, the FDA notified ITI that there will be no clinical hold and that ITI may now proceed with its clinical trial in June for JRC-LAMP-vax in Atlanta with subjects sensitive to Japanese Red Cedar pollen.

JRC-LAMP-Vax is a plasmid-based DNA vaccine that will be studied for the treatment of patients with rhino-conjunctivitis (runny nose) symptoms caused by allergic reaction to Japanese red cedar pollen. Almost 45% of the Japanese people are allergic to Japanese red cedar pollen. In North America, there is allergic rhinitis to mountain cedar pollen, which is 80% cross-reactive with Japanese red cedar pollen allergen.  ITI intends to partner with a Japanese pharmaceutical company for studies in Japan and will seek FDA approval of the vaccine in the US.

 

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Morning Read: VC sees opportunities in areas where Pharma is pulling back

 

Pharma Dollars

Counter-intuitive as it may be, investing in areas that pharma is abandoning could yield great returns for investors. Just look at anti-bacterials in the ’90s and 2000s, says VC Bruce Booth in a Forbes column. So where should investors be looking today? Neuroscience, heart failure and obesity.

The shortage of cancer drugs that’s plagued hospitals for almost two years now has eased, although not completely, according to cancer doctors.

A recent study by Johns Hopkins researchers brings a reality check to the potential (and the limits) of genome sequencing in predicting disease.

 

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To Neuroscience Drug Discovery and Preclinical Development Researchers:

 

ninds-logo

I would like to bring to your attention that the Office of Translational Research (OTR) at the National Institute of Neurological Disorders & Stroke (NINDS) is seeking to fill two senior program leadership positions in neuroscience drug and device development. The two position descriptions are described briefly below and more detailed job descriptions are attached. Please forward this announcement to qualified candidates. We will be at the Biotechnology Industry Organization (BIO) meeting in Boston next week, and would be happy to meet to discuss these positions. To meet at BIO or for more information please contact Dr. Eric Nelson (eric.nelson2@nih.gov) in OTR.

 

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Government Unveils First Map Of All The Germs In The Human Body – Forbes

 

germs-map

Today, in two of the world’s top medical journals, scientists are publishing the results of a $173 million government-funded project to sequence the vast bulk of bacteria, fungi, and viruses in and on the human body.

The results might at first seem anticlimactic. There’s no news about which germs cause or prevent disease, or even a clear message about how they make people different from one another. What we know is there are a lot of them. We have ten times as many microbial cells in our body as human ones, and though they are tiny, that still means that a 200-pound man is carrying two to six pounds of microbes, mostly bacteria. And there are tantalizing hints that they might play a role in all sorts of diseases. Patients who are at risk for difficult-to-treat hospital infections might have a particular kind of bacteria in their digestive systems; those who are obese might have another; children who can’t get enough nutrition might have a third.

 

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Opinion: What’s Wrong with COI? | The Scientist

 

financial-coi

Advances in medical and surgical care are hard-won. They require rigorous, carefully interpreted laboratory research. Equally important is the painstaking clinical work to translate basic discoveries into useful diagnostics, drugs, and devices.  Despite the odds, the achievements made in the past half century are unmistakable: a 50 percent reduction in cardiovascular mortality despite an epidemic of obesity; a dramatically decreased cancer mortality rate; and the conversion of AIDS from a death sentence to survival with good life quality.

The key to such success has been the growing number and complexity of collaborations between academics, physicians, regulatory agencies, and—not least—industry. Unfortunately, over the past 20 years, a mania has taken hold that discounts the social value of collaboration and has mounted an inquisition against it, encapsulated by the epithet “financial conflict of interest (fCOI).” Critics’ unwarranted allegations that such conflicts cause bias have limited the sources of intellect that can contribute to a given project.

 

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CMS ANNOUNCES PRIVATE-SECTOR COMMITMENTS TO IMPROVE PRIMARY CARE FOR PATIENTS, SAVE MONEY FOR MEDICARE

 

CMS

In a strong show of support for more effective, more affordable, higher quality health care, 45 commercial, federal and State insurers in seven markets today pledged to work with the Centers for Medicare & Medicaid Services (CMS) to give more Americans access to quality health care at lower cost.

Under the Comprehensive Primary Care initiative, CMS will pay primary care practices a care management fee, initially set at an average of $20 per beneficiary per month, to support enhanced, coordinated services.  Simultaneously, participating commercial, State, and other federal insurance plans are also offering an enhanced payment to primary care practices that provide high-quality primary care.  

 

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NCI: SBIR & STTR – Resource Center – Innovative Partnerships for Commercializing Health IT

 

SBIR STTR

The National Cancer Institute (NCI) recently announced a new Program Announcement, aimed at accelerating the development and commercialization of consumer health information technology products that translate the behavioral and communication science evidence base for the prevention and control of cancer and other chronic diseases. The NCI and the National Library of Medicine (a co-funding partner) are interested in supporting the development and dissemination of evidence-based health information technology (health IT) products that have the potential to:

  • Prevent or reduce the risk of cancer 
  • Facilitate patient-provider communication and/or 
  • Improve disease outcomes in consumer and clinical settings

A non-exclusive list of product examples relevant to the FOA are provided below.

 

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HHS harnesses the power of health data to improve health

 

DHHS

The Department of Health and Human Services (HHS), along with the Institute of Medicine (IoM) and other members of the Health Data Consortium, are co-hosting the third annual “Datapalooza” focusing on innovative applications and services that harness the power of open data from HHS and other sources to help improve health and health care.

The Health Data Initiative Forum III is featuring more than 100 new or updated solutions, up from 45 solutions last year, that help serve the needs of consumers, health care providers, employers, public health leaders, and policy makers.

“The innovators present today are a great example of how data and technology can be used in powerful ways to help consumers and providers improve health,” said HHS Secretary Kathleen Sebelius. “We’re not just creating new technology, but we’re empowering Americans to make better decisions about health and health care by putting information at their fingertips.”

 

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About BHI

 

BioHealth Innovation (BHI) is a regionally-oriented, private-public partnership functioning as an innovation intermediary focused on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in Maryland.

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