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Regeneron Builds a Database of Human Knockouts in Search for Drug Clues – MIT Technology Review

By November 19, 2014May 22nd, 2025No Comments

genes-dna-sxc

Ten years ago, scientists discovered that some people are naturally missing working copies of a gene known as PCSK9. The consequences of the mutation were extraordinary. These people, including a Texas fitness instructor, a woman from Zimbabwe, and a 49-year-old Frenchman, had almost no bad cholesterol in their blood. Otherwise, they were perfectly normal.

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