The Biomedical Research Institute (BRI), founded in Rockville, MD in 1968, is a not-forprofit research institute that emphasizes basic research in schistosomiasis. BRI expanded its subsidiaries in 1985 to include the Association of Entrepreneurial Science (AES), an incubator for startup scientific companies that brings scientists and basic research findings into the realm of commercial markets. AES brings together all the accompanying business skills required for profit making entrepreneurs to bring scientific products and services to the marketplace.