BHI Weekly News Archives

What’s happening? ARPA-H is launching the Emerging Health Innovators (EHI) Initiative to increase access to government research funding for early career researchers and community health innovators to address health care gaps in the U.S.

Why it matters? Early career researchers and community health innovators, including those from minority-serving institutions and community-based organizations, will now have more opportunities to pursue bold and technically risky R&D projects, but who have been unable to take these leaps using traditional funding opportunities.

U.S. Pharmacopeia (USP) is currently seeking Expert Volunteers from diverse professional backgrounds to contribute to its vital mission of safeguarding the quality of medicines, dietary supplements, and food ingredients. For over 200 years, USP has maintained trust in healthcare products through rigorous standards, and now they are calling on scientists, healthcare professionals, regulatory experts, and academicians to join them for the 2025–2030 cycle.

Volunteering with USP offers a unique opportunity to work alongside global experts from academia, industry, and regulatory bodies to help review and revise USP standards. These standards are essential for public health, legally recognized in the U.S., and used in over 150 countries. Volunteers will lend their expertise to address emerging health concerns, build awareness, and reduce the risk of substandard healthcare products. As a part of an Expert Committee, you’ll help shape global healthcare and contribute to ensuring that consumers worldwide have access to safe and reliable products.

With COVID-19 still spreading and mpox emerging as a public health emergency of international concern, the National Institutes of Health (NIH) is upping preparations for future pandemics.

The Research and Development of Vaccines and Monoclonal Antibodies for Pandemic Preparedness network (ReVAMPP) will research pathogens that currently lack effective treatments and vaccines, with the NIH’s National Institute of Allergy and Infectious Diseases (NIAID) committing up to $100 million per year to the effort so long as funds are available, the agency announced Sept. 13.

“In the wake of the COVID-19 pandemic and ongoing outbreaks of emerging infectious diseases, the need for robust pandemic preparedness is evident,” NIAID Director Jeanne M. Marrazzo, M.D., said in the release. “The ReVAMPP network will enable researchers to fill key knowledge gaps and identify strategies to develop safe and effective medical countermeasures for targeted virus families before the need becomes critical.”

WILMINGTON, Del., September 20, 2024 – FLUMIST® has been approved in the US as the only self-administered influenza vaccine. FLUMIST, a needle-free nasal spray, was approved to be self-administered by adults up to 49 years of age or administered by a parent/caregiver to individuals 2-17 years of age.1

The approval by the US Food and Drug Administration (FDA) was based on a comprehensive submission, which included results from a usability study demonstrating that individuals over 18 years of age could self-administer or administer FLUMIST to eligible individuals 2-49 years of age.1

TOKYO, September 18, 2024 — Astellas Pharma Inc. (TSE: 4503, President and CEO: Naoki Okamura, “Astellas”) today announced that DIGITIVA™, a non-invasive digital health solution for heart failure management, has been listed with the U.S. Food and Drug Administration (FDA). DIGITIVA is classified as a Class I Software as a Medical Device (SaMD) and is exempt from 510(k) premarket submission*. DIGITIVA is the first digital health offering from Astellas in the U.S.

DIGITIVA is designed to place patients impacted by heart failure at the center of their care, allowing them to take a more active role in managing their health while working in partnership with their care team. DIGITIVA is comprised of three components: the CORE 500™ Digital Stethoscope developed by Eko Health Inc., a smartphone app designed for heart failure patients and built on the Welldoc, Inc. platform, bolstered by educational content from the American Heart Association, and a dedicated clinical review team. The DIGITIVA clinical review team triages patient data, including previously elusive biomarkers specific to heart failure, and notifies the patient’s treating physician when certain signals are present that may indicate the patient would benefit from intervention, with the goal of impacting clinical outcomes such as acute decompensation events and re-hospitalizations.

RICHMOND, Va., Sept. 17, 2024 /PRNewswire/ — Activation Capital proudly announces the launch of Start-the-Journey, a new BioHealth Pre-Accelerator designed to equip early-stage biotech and life science entrepreneurs with the knowledge and tools to build successful startups. Powered by Fat Robin Consulting, this innovative program supports founders in the initial phases of their entrepreneurial journey, preparing them for more advanced initiatives like Activation Capital’s Frontier BioHealth, launched earlier this year to support scaling advanced-stage startups.

COLUMBIA, Md., Sept. 17, 2024 /PRNewswire/ — The Maryland Stem Cell Research Commission (MSCRC) announces the allocation of approximately $4.5 million in new grant awards to advance stem cell research and technology. These grants will drive innovative research with the potential to deliver life-saving treatments and transformative cures for patients with a variety of medical conditions.

This award has been awarded to 11 accomplished scientists from Maryland-based institutions and companies. The awardees include researchers from renowned academic institutions such as Johns Hopkins University and the University System of Maryland, as well as pioneering companies such as Therapative Inc. and Caleo Biotechnologies, Inc. Non-profit organizations, including Regenerative Orthopedics and Sports Medicine, LLC are also among the recipients. The grants will support critical research into treatments for brain diseases such as Alzheimer’s and dementia, blindness, autoimmune diseases, inflammatory bowel disease and orthopedic conditions, among others.

Maryland-based business has the potential to reshape the ophthalmology and neurology sectors

COLUMBIA, Md., (September 10, 2024) — TEDCO, Maryland’s economic engine for technology companies, announced a recent $200,000 Builder Fund investment in JuneBrain Inc., a biotechnology company. TEDCO’s Pre-Seed Builder Fund is part of TEDCO’s Social Impact Funds, which were created to engage and invest in economically underserved founders and communities.

“JuneBrain was originally started to creatively support patients and those who care for them,” said Dr. Samantha Scott, founder and CEO. “TEDCO’s continued investments in us have helped our goals and unique strategies come to fruition.”

COLLEGE PARK, Md., September 11, 2024–(BUSINESS WIRE)–IonQ (NYSE: IONQ), a leader in the quantum computing industry, and the University of Maryland (UMD), an international powerhouse in quantum research and applications, today announced an agreement to expand their partnership to provide state-of-the-art quantum computing access at the National Quantum Lab at Maryland (QLab). QLab provides UMD-affiliated students, faculty, researchers, staff and partners with an unprecedented opportunity to work closely with IonQ’s scientists and engineers as they gain experience with industry-leading trapped ion quantum computers.

QLab, a first-of-its-kind lab for quantum research and development, has supported multiple cohorts of undergraduate interns, multiple academic research projects, and multiple companies within UMD’s Quantum Startup Foundry and Mid-Atlantic Quantum Alliance. Workshops have also been held for government partners such as NASA Goddard Space Flight Center, as well as other events and tours for government and international visitors.

The U.S. Economic Development Administration (EDA) is accepting applications for its FY24 $50 million Build to Scale program to support organizations that strengthen entrepreneurial ecosystems to support entrepreneurs as they build and scale technology-driven businesses—and the employees in the new, good jobs they create—to make and deliver new technology products and services. [Read Today’s Blog Post] 

Build to Scale (B2S) grants fund programs that support innovators, entrepreneurs, and startups transforming ideas into the critical, emerging technologies of the future.  

Emmes, part of Emmes Group, today announced they will provide a Clinical Coordinating Center for the NIH’s National Institute on Drug Abuse Clinical Trials

ROCKVILLE, Md., Sept. 4, 2024 /PRNewswire/ — Emmes, part of Emmes Group, a leading specialty tech-enabled global contract research organization (CRO), has been selected by the National Institutes of Health’s (NIH) NIDA [National Institute of Drug Abuse] to support their Clinical Trials Network (CTN) for a multi-task, IDIQ contract.

GAITHERSBURG, Md., Sept. 09, 2024 (GLOBE NEWSWIRE) — Cartesian Therapeutics, Inc. (NASDAQ: RNAC) (the “Company”), a clinical-stage biotechnology company pioneering mRNA cell therapy for autoimmune diseases, today announced that the U.S. Food and Drug Administration (FDA) has granted Rare Pediatric Disease Designation to Descartes-08 for the treatment of juvenile dermatomyositis (JDM).

Descartes-08, Cartesian’s lead mRNA cell therapy candidate, is an autologous mRNA-engineered chimeric antigen receptor T-cell therapy (mRNA CAR-T) product candidate targeting B-cell maturation antigen (BCMA). Descartes-08 is designed to be administered without preconditioning chemotherapy and does not use integrating vectors.

The Maryland Department of Commerce has officially opened the 2025 Biotechnology Investment Incentive Tax Credit (BIITC) program. Qualified Maryland Biotechnology Companies (QMBCs) can submit Form B applications starting on August 20, 2024, while investors can submit Form A applications starting September 3, 2024. The program offers income tax credits ranging from 33% to 75% of eligible investments, depending on the QMBC’s location and specific program qualifications.

Enhanced credits are available for investors in Opportunity Zones and RISE Zones, with higher tax credits based on eligibility. Registration for the investor queue opens on September 24, 2024, and applications are processed on a first-come basis, with limited funding available. Be sure to apply early through the Commerce online system to take advantage of these tax benefits. For more information, please visit the official BIITC program page.

The U.S. Economic Development Administration (EDA) is accepting applications for its FY24 $50 million Build to Scale program to support organizations that strengthen entrepreneurial ecosystems to support entrepreneurs as they build and scale technology-driven businesses—and the employees in the new, good jobs they create—to make and deliver new technology products and services. [Read Today’s Blog Post] 

Build to Scale (B2S) grants fund programs that support innovators, entrepreneurs, and startups transforming ideas into the critical, emerging technologies of the future.  

Johns Hopkins Technology Ventures (JHTV) has proudly released its FY24 Annual Report, marking ten years of exceptional growth in innovation and entrepreneurship. The report highlights JHTV’s significant achievements, including a fourfold increase in venture investments and a tripling of annual licensing revenue. These accomplishments underscore JHTV’s critical role in translating groundbreaking research into impactful technologies.

The report also celebrates the establishment of the Pava Marie LaPere Center for Entrepreneurship, which continues to nurture student and community innovation at Johns Hopkins. In addition to these milestones, JHTV has spearheaded collaborations, secured substantial funding, and supported the growth of new startups, further solidifying its position as a leader in academic technology transfer.

GAITHERSBURG, Md., Sept. 03, 2024 (GLOBE NEWSWIRE) — Cartesian Therapeutics, Inc. (NASDAQ: RNAC) (the “Company”), a clinical-stage biotechnology company pioneering mRNA cell therapy for autoimmune diseases, today announced that the first patient has been dosed in its first-in-human Phase 1 trial of Descartes-15, the Company’s next-generation autologous anti-B cell maturation antigen (BCMA) mRNA-engineered chimeric antigen receptor T-cell therapy (mRNA CAR-T).

GAITHERSBURG, Md., Aug. 30, 2024 /PRNewswire/ — Novavax, Inc. (Nasdaq: NVAX), a global company advancing protein-based vaccines with its Matrix-M™ adjuvant, today announced the Novavax COVID-19 Vaccine, Adjuvanted (2024-2025 Formula) (NVX-CoV2705) has received Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration (FDA) for active immunization to prevent COVID-19 in individuals aged 12 and older. Novavax’s vaccine is included in the recommendations issued by the U.S. Centers for Disease Control and Prevention (CDC) on June 27, 2024.

ARLINGTON, Va., Aug. 28, 2024 /PRNewswire/ — OxiWear, a pioneering company in wearable health technology, is proud to announce that it has received clearance from the U.S. Food and Drug Administration (FDA) for its cutting-edge oxygen monitoring device. This certification marks a significant milestone in OxiWear’s mission to revolutionize patient care and enhance the quality of life for individuals with chronic diseases.

OxiWear is a cutting-edge ear pulse oximeter designed for continuous, real-time measurement of blood oxygen saturation (SpO₂) and pulse rate. This device provides unmatched accuracy and convenience while still and during motion, across all skin types, within clinical and home environments. Unlike traditional methods, OxiWear ensures that patients and healthcare providers have constant access to important oxygen saturation data. The continuous data collection capability is vital for the early detection of hypoxemia (low oxygen levels), offering prompt haptic and emergency messaging alerts that can potentially save lives.

By Sara Gilgore – Staff Reporter, Washington Business Journal Aug 21, 2024 – Sally Allain, the inaugural head of Johnson & Johnson Innovation’s D.C. incubator, has left her position after more than four years — to grow Virginia Tech’s health sciences research enterprise.

Allain, a longtime J&J exec who built up and led the local JLabs hub that planted roots on Children’s National Hospital’s Walter Reed campus in spring 2019, stepped away this month, announcing her departure in a LinkedIn post. She’ll start with Virginia Tech next week as chief health sciences growth and innovation officer, a newly created position charged with spinning out technology companies and tapping big-name partners across sectors.

HJF, Montgomery County, Maryland & BioBuzz

We are teaming up to bring the research community a new and exciting opportunity – the HJF Networking and Educational Series. Each quarter, a new topic will be presented in HJF’s state-of-the-art Conference Facility located at HJF Headquarters, followed by complimentary food and drinks.

Join us at 4 p.m. on September 9, 2024

https://www.hjf.org/networking-educational-series

Questions? Send an Email to: Linda Yaswen-Corkery

Want to Learn the Ins & Outs of the FDA Approval Process?

Join us for an informative FDA Panel, moderated by HJF’s Scientific  Employee Resource Group, followed by networking with Montgomery County life science colleagues.

Date: September 9, 2024
Time: 4-7 p.m.
Location: HJF Conference Facility
6720A Rockledge Drive
Bethesda, MD 20817

COLUMBIA, Md., (August 26, 2024) — TEDCO, Maryland’s economic engine for technology companies, announced a recent $200,000 Pre-Seed Builder Fund investment in Simmbion, LLC. Businesses receiving an investment from TEDCO’s Pre-Seed Builder Fund, housed under TEDCO’s Social Impact Funds, receive access to a variety of benefits designed to nurture business growth.

“The promise of biologic drugs has been hampered by the need for frequent injections and cold-chain logistics,” said Derese Getnet, CEO of Simmbion. “Through the assistance of TEDCO, Simmbion is working to eliminate the need for recurrent needle-based administration of these drugs (and all the associated cold-chain). In success, our approach will transform adherence to treatment for diabetes, obesity, rare genetic diseases and cancer.”

FALLS CHURCH, Va.–(BUSINESS WIRE)–Retension Pharmaceuticals, Inc. is pleased to announce the successful closing of its Series A $10.4 million financing round to initiate a well-powered and controlled Phase 2 clinical study in patients with hypertension uncontrolled on two or more antihypertensives.

Retension Pharmaceuticals is a clinical-stage therapeutic development company focused on developing innovative treatments for hypertension and cardiovascular disease. The company’s lead drug candidate, RTN-001, a second generation PDE5 inhibitor, was designed to target the tissues of the higher vasculature by the company’s CSO and Co-Founder, Dr. Paul Sweetnam, overcoming the limitations of first generation PDE5 inhibitors in the hypertension space. According to the WHO, it is estimated that hypertension affects 1.28 billion adults worldwide, of whom only 21% have their hypertension fully under control. In prior clinical trials, RTN-001 has been studied in over 265 human subjects, including two Phase 2 studies in patients with uncontrolled hypertension. In these studies, RTN-001 was shown to be well tolerated and demonstrated clinically significant blood pressure lowering effects.

The 7th Annual Investment Conference, scheduled for September 19th during the BioHealth Capital Region Week at US Pharmacopeia in Rockville, MD, offers a unique platform for companies and investors. Attendees will have the opportunity to create detailed profiles and schedule face-to-face meetings throughout the day to discuss potential collaborations and funding. Simultaneously, the auditorium will feature a series of quick pitches, providing selected companies and some investors with 7 minutes each to introduce themselves and present their ideas in front of an audience of peers and potential partners.

Why Investors Should Attend

For investors, this conference is an indispensable opportunity to access a curated selection of startups with groundbreaking ideas poised for investment. It offers a chance to engage directly with founders, understand their business models, and evaluate their potential in person. Investors can gain early insights into emerging technologies and trends, potentially leading to profitable investment opportunities and partnerships. Register Now.

Why Companies Should Attend

For companies, the Investment Conference is a vital avenue to meet face-to-face with leading investors actively looking to fund innovative projects and businesses. It provides a platform not only for potential funding but also for valuable feedback and advice on scaling their operations. The quick-pitch sessions offer companies a chance to capture attention, showcase their innovations, and articulate their vision to a room full of potential backers. Register Now.

BALTIMORE, MARYLAND, US, August 12, 2024 /EINPresswire.com/ — The study, “Advanced Prediction of Respiratory Depression Episodes with the Linshom Continuous Predictive Respiratory Sensor”, completed enrollment of 508 patients well ahead of schedule.

“Preliminary analysis of the data shows that Linshom Medical’s sensor detects respiratory depression 12 minutes before current systems employed”, said Richard Urman, MD, MBA, the principal investigator of the study. “This gives health care providers additional time to take action and intervene before a crisis develops”.

Based on AEGEAN Phase III trial results which showed Imfinzi-based regimen reduced the risk of recurrence, progression or death by 32% vs. neoadjuvant chemotherapy alone

AstraZeneca’s Imfinzi (durvalumab) in combination with chemotherapy has been approved in the US for the treatment of adult patients with resectable early-stage (IIA-IIIB) non-small cell lung cancer (NSCLC) and no known epidermal growth factor receptor (EGFR) mutations or anaplastic lymphoma kinase (ALK) rearrangements. In this regimen, patients are treated with Imfinzi in combination with neoadjuvant chemotherapy before surgery and as adjuvant monotherapy after surgery.

The 7th Annual Investment Conference, scheduled for September 19th during the BioHealth Capital Region Week at US Pharmacopeia in Rockville, MD, offers a unique platform for companies and investors. Attendees will have the opportunity to create detailed profiles and schedule face-to-face meetings throughout the day to discuss potential collaborations and funding. Simultaneously, the auditorium will feature a series of quick pitches, providing selected companies and some investors with 7 minutes each to introduce themselves and present their ideas in front of an audience of peers and potential partners.

Why Investors Should Attend

For investors, this conference is an indispensable opportunity to access a curated selection of startups with groundbreaking ideas poised for investment. It offers a chance to engage directly with founders, understand their business models, and evaluate their potential in person. Investors can gain early insights into emerging technologies and trends, potentially leading to profitable investment opportunities and partnerships. Register Now.

Why Companies Should Attend

For companies, the Investment Conference is a vital avenue to meet face-to-face with leading investors actively looking to fund innovative projects and businesses. It provides a platform not only for potential funding but also for valuable feedback and advice on scaling their operations. The quick-pitch sessions offer companies a chance to capture attention, showcase their innovations, and articulate their vision to a room full of potential backers. Register Now.

BALTIMORE, MARYLAND, US, August 12, 2024 /EINPresswire.com/ — The study, “Advanced Prediction of Respiratory Depression Episodes with the Linshom Continuous Predictive Respiratory Sensor”, completed enrollment of 508 patients well ahead of schedule.

“Preliminary analysis of the data shows that Linshom Medical’s sensor detects respiratory depression 12 minutes before current systems employed”, said Richard Urman, MD, MBA, the principal investigator of the study. “This gives health care providers additional time to take action and intervene before a crisis develops”.

GAITHERSBURG, Md., July 31, 2024 (GLOBE NEWSWIRE) — Today, Emergent BioSolutions Inc. (NYSE: EBS) announced the sale of RSDL^® (Reactive Skin Decontamination Lotion) kit to SERB Pharmaceuticals, a global pharmaceutical company, for a purchase price of approximately $75 million. In addition, SERB will pay Emergent a $5 million payment upon achievement of a milestone related to the sourcing of a certain component of RSDL^®. The transaction has signed and closed simultaneously. 

In addition, SERB will acquire and maintain operations of Emergent’s leased manufacturing facility in Hattiesburg, Mississippi, and several site-based employees who support RSDL^® will join SERB. SERB will also acquire the RSDL^® product inventory as part of the transaction and will assume certain related contracts. Emergent’s Winnipeg facility will continue to manufacture and supply bulk lotion to SERB under a long-term supply agreement between the two companies.

In this episode of BioTalk, Rich Bendis, President and CEO of BioHealth Innovation, Inc., welcomes guests from ARPA-H: Craig Gravitz, Director of the Project Accelerator Transition Innovation Office (PATIO), and Jenica Patterson, Ph.D., Portfolio Lead at ARPA-H. Together, they provide a comprehensive overview of ARPA-H’s mission and innovative programs.

Craig Gravitz and Jenica Patterson share their educational and career backgrounds, setting the stage for a discussion about ARPA-H and its various initiatives. They provide insights into how ARPA-H differentiates itself from other agencies like HHS and NIH, while also highlighting their collaborative efforts.

Listen now via your favorite podcast platform:

Apple: https://apple.co/4dy5wmS
Spotify: https://spoti.fi/3yDIV9k 
Amazon Music: https://amzn.to/3AcL3FI 
TuneIn: https://bit.ly/3LV54Dg

ROCKVILLE, Md., July 30, 2024—The Montgomery County Council voted today to approve the Planning Board Draft of the Great Seneca Plan: Connecting Life and Science with revisions. The plan covers 4,330 acres located in the heart of the I-270 Corridor between the cities of Gaithersburg and Rockville and the town of Washington Grove. The Plan makes recommendations to strengthen the economic competitiveness of the Life Sciences Center, guide future developments, and transform public spaces and amenities in the area to provide valuable links and social spaces. 

“The Great Seneca Science Corridor is one of Montgomery County’s most important strategic areas, as the heart of our globally recognized biohealth industry with world-class research, education, and health care facilities,” said Council President Andrew Friedson who also chairs the Planning, Housing and Parks (PHP) Committee. “This plan builds on that strength by creating a more sustainable and vibrant community with greater connectivity to improve quality of life and economic competitiveness.”

ROCKVILLE, Md., July 31, 2024 (GLOBE NEWSWIRE) — Theriva™ Biologics, Inc. (NYSE American: TOVX), a diversified clinical-stage company developing therapeutics designed to treat cancer and related diseases in areas of high unmet need, today announced that the U.S. Food and Drug Administration (FDA) granted Rare Pediatric Drug Designation (RPDD) for VCN-01 for the treatment of retinoblastoma. VCN-01, Theriva’s lead product candidate, is a systemic, selective, stroma-degrading oncolytic adenovirus. Previously, the FDA granted orphan drug designation to VCN-01 for treatment of retinoblastoma.

HONG KONG, GERMANTOWN, Md. and SUZHOU, China, July 31, 2024 /PRNewswire/ — Sirnaomics Ltd. (the “Company“, Stock Code: 2257.HK, together with its subsidiaries, the “Group” or “Sirnaomics“), a leading biopharmaceutical company engaging in discovery and development of advanced RNAi therapeutics, today announced a partnership with Gore Range Capital LLC (“Gore Range Capital“) (Dallas, TX, USA) for establishment of a joint venture, Sagesse Bio, Inc., to advance its novel RNAi therapeutic products into aesthetic medicine.

GAITHERSBURG, Md., July 31, 2024 (GLOBE NEWSWIRE) — Today, Emergent BioSolutions Inc. (NYSE: EBS) announced the sale of RSDL^® (Reactive Skin Decontamination Lotion) kit to SERB Pharmaceuticals, a global pharmaceutical company, for a purchase price of approximately $75 million. In addition, SERB will pay Emergent a $5 million payment upon achievement of a milestone related to the sourcing of a certain component of RSDL^®. The transaction has signed and closed simultaneously. 

In addition, SERB will acquire and maintain operations of Emergent’s leased manufacturing facility in Hattiesburg, Mississippi, and several site-based employees who support RSDL^® will join SERB. SERB will also acquire the RSDL^® product inventory as part of the transaction and will assume certain related contracts. Emergent’s Winnipeg facility will continue to manufacture and supply bulk lotion to SERB under a long-term supply agreement between the two companies.

GAITHERSBURG, Md., July 30, 2024 (GLOBE NEWSWIRE) — Today, Georgiamune Inc., a privately held, clinical-stage biotechnology company, announced that the first patient has been dosed with GIM-531 in a first-in-human, phase 1 clinical trial for the treatment of advanced cancer patients. GIM-531 development focuses on indications that are currently not addressed with existing or available immunotherapies including anti-PD-1 antibodies. It is an oral therapy that is a first-in-class selective T regulatory cell inhibitor.

ROCKVILLE, Md., July 23, 2024 /PRNewswire/ — Emmes Group, a leading specialty tech-enabled global contract research organization (CRO), today announced a multi-year strategic partnership with Miimansa AI. A critical pillar of the partnership, aimed at revolutionizing clinical research at Emmes, is the acquisition of Miimansa’s Clinical Entity Modeling tools based on advanced large language modeling (LLM) techniques and generative AI.

Artificial intelligence (AI) promises to transform all aspects of healthcare including clinical research. Emmes Group is rapidly maturing its technology platform, Veridix AI, and Miimansa’s Clinical Entity Modeling technology will serve as a critical building block to accelerate the development of state-of-the-art automated text processing solutions tailored for clinical research.

July 25, 2024 / By Laura Powers: Researchers in George Mason University’s Center for Infectious Disease Research (CIDR) and Tulane National Primate Research Center conducted a breakthrough proof-of-concept study, published in Nature’s Gene Therapy, that found a human immunodeficiency virus (HIV)-like virus particle that could cease the need for lifelong medications. Scientists have made great strides in the treatment of HIV over the past few decades, yet those with the virus must still take antiretroviral therapy for life as the disease is difficult to eradicate. 

CIDR researchers led by Yuntao Wu, a professor in George Mason’s School of Systems Biology and the principal investigator of the National Institutes of Health-funded study, developed a special HIV-like virus particle, called HIV Rev-dependent lentiviral vector, that uses an HIV protein, Rev, as a trigger to selectively target and activate therapeutic genes in HIV-infected cells.

The Mason team, including Brian Hetrick, Mark Spear, Jia Guo, Huizhi Liang, Yajing Fu, Zhijun Yang, and Ali Andalibi, has been developing the HIV Rev-dependent vector technology since 2002. 

According to Wu, patients need to take medications for the rest of their lives because of the persistence of HIV reservoirs, which are infected immune cells harboring the virus. Currently, antiretroviral therapy used by patients can effectively block the virus but cannot eliminate the viral reservoirs. Experimental approaches such as “shock and kill” and “block and lock” of the reservoirs have been in development to either eliminate or silence viral reservoirs.

Click here to continue reading. 

On July 25, 2024, the FDA will host a significant virtual public meeting, “Home as a Health Care Hub – Stakeholder Listening Session,” from 12:00 PM to 4:00 PM ET. This session aims to explore how integrating home environments into the healthcare system can enhance health equity and patient care. The FDA seeks input from various stakeholders to identify both barriers and opportunities in this integration. Additionally, the initiative includes developing VR prototypes for managing conditions like diabetes.

Stakeholders are encouraged to register, participate, and submit comments or presentations ahead of the event.

For more information and registration details, Click here.

The National Cancer Institute’s (NCI) Technology Transfer Center invites you to the 2024 Technology Showcase on September 4th, at the Frederick National Laboratory Advanced Technology Research Facility in Frederick, MD. This free, in-person event will present a remarkable lineup of cutting-edge technologies ready for commercialization. Industry experts will share their insights through engaging presentations, panel discussions on successful collaborations, and a competitive poster session highlighting innovative research.

Attendees will have the opportunity to connect with industry leaders, investors, and entrepreneurs, fostering meaningful networking and potential partnerships. The keynote speaker, Steven Walker, will deliver a compelling address on the future of biotechnology and its impact on cancer research.

The event is an exceptional platform for biotech stakeholders to discover new technologies and explore collaborative ventures. Whether you’re a company, investor, or entrepreneur, the 2024 Technology Showcase offers invaluable insights and connections.