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NHLBI Funding Opportunity Announcements, June 18, 2013

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The following funding opportunity announcements from the NHLBI or other components of the National Institutes of Health, might be of interest:

NIH Guide Notice:

Request for Information:

  • Request for Information (RFI): Input on Administration of the NIH-Industry Pilot Program Discovering
    The goal of this Request for Information (RFI) is to collect feedback from the biomedical research community, pharmaceutical companies, and other members of the public about the “NIH-Industry Pilot Program: Discovering New Therapeutic Uses for Existing Molecules” initiative and the application process. NCATS is interested in feedback from researchers and institutions that submitted an application, considered submitting an application but did not, and/or would be interested in submitting an application in the future. NCATS is also interested in feedback from existing and potential pharmaceutical partners.
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Defense Department Establishes First Brain Tissue Repository In Bethesda – BethesdaNow

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The Department of Defense last week announced the establishment of the world’s first brain tissue repository on the Walter Reed Campus to help researchers better understand traumatic brain injury (TBI).

TBI is common among veterans of the wars in Afghanistan and Iraq, which led to the opening of The Center for Neuroscience and Regenerative Medicine Brain Tissue Repository for Traumatic Brain Injury at the Uniformed Services University on the campus.

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University Economic Development Association (UEDA) seeks nominations for 2013 Awards of Excellence – University Economic Development Association

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The University Economic Development Association (UEDA) is currently seeking nominations for its annual Awards of Excellence program, which recognizes leading edge university-based economic development initiatives from across the country. The Awards of Excellence Program recognizes higher education institutions and their partners who are transforming their campuses into engines of economic prosperity through creative initiatives in five categories: 

  1. Community Connected Campus: initiatives that promote the physical development of quality connected campuses and their surrounding communities;
  2. Research and Analysis: initiatives that enhance the capacity of colleges and universities to provide new forms of research and tools for community, economic and workforce development practitioners;
  3. Leadership and Collaboration: initiatives that support the development of collaborative economic development strategies and the leaders required to implement them;
  4. Innovation and Entrepreneurship: initiatives designed to support startups, high-growth companies and clusters within a region; and
  5. Talent Development: initiatives that promote the development of 21st-century skills.
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FastForward Opening Celebration June 27 – LAST CHANCE TO RSVP

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June 27th, 3:30-5:30pm

Join Nicholas P. Jones, Benjamin T. Rome Dean, Whiting School of Engineering to celebrate the launch of FastForward.

There are a few spots left.
RSVP today!
410-516-8723 / engineering@jhu.edu

Get a preview of the innovative technologies created by Johns Hopkins faculty, postdoctoral fellows, and students in the FastForward accelerator and see examples of entrepreneurship from across the university. Learn how FastForward, a unique innovation system, can increase the probability of a startup’s success.

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Ocular Proteomics, a National Retina Institute Spin Out, Relocates to UM BioPark

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The University of Maryland (UM) BioPark announced today that Ocular Proteomics, LLC (OPL), a startup biotechnology company leveraging a new class of biomarkers found in vitreous fluid of the eye to more accurately diagnose and treat retinal diseases, has recently relocated to Building One of the BioPark from Baltimore County. Led by world-renowned and internationally respected retinal surgeon Bert M. Glaser, M.D., OPL is a spin out of the National Retina Institute. OPL’s move to the BioPark comes on the heels of the company’s $1.2 million dollar Small Business Innovation in Research (SBIR) phase 2 grant from the National Institutes of Health. In its new space, OPL will be conducting the research phase of a multi-center clinical trial, which will include 200 patients with macular degeneration.

Said Jim Hughes, President, Research Park Corporation, University of Maryland Baltimore, “The BioPark has once again attracted an innovative and important start-up to our location. We’re pleased to welcome Dr. Glaser and Ocular Proteomics to our roster of commercial tenants. Dr. Glaser founded Ocular Proteomics to use personalized medicine to drastically change the way blinding diseases are diagnosed and treated.”

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AstraZeneca: MedImmune, AstraZeneca’s Biologics Arm, and NGM Biopharmaceuticals Announce Agreement to Discover and Develop Therapies for Diabetes and Obesity

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AstraZeneca (STO:AZN)(LSE:AZN) today announced that MedImmune, its global biologics research and development arm, and NGM Biopharmaceuticals, Inc. have entered into an exclusive agreement to discover, develop and commercialise novel therapeutics from NGM’s enteroendocrine cell (EEC) programme for the treatment of type 2 diabetes and obesity.

EECs represent less than 1% of all gastrointestinal (GI) cells, but produce virtually all of the known GI hormones, including GLP-1. EECs are an underexplored source of novel hormones that could play a major role in the positive and negative regulation of metabolism and glucose homeostasis. NGM has established a proprietary platform capable of isolating and analysing EECs in order to identify novel secreted peptide hormones that are potentially linked to the profound metabolic effects of bariatric surgery and serve as potential targets for the treatment of metabolic diseases.

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What are the top 5 ways physicians use tablets and smartphones in their medical practice? – MedCity News

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It’s a popular sport among startups and the mobile vendor community to figure out what physicians are willing to do on their tablets and smartphones. It has to be said that some of them have come up with some pretty compelling approaches to deepen the relationship between physicians and their mobile devices.

But what is really going on in their practices? In two studies generated from a survey by AmericanEHRPartners of 1,400 with responses from about 696 physicians and 150 allied health professionals has uncovered some interesting information. AmericanEHRPartners was formed in 2010 by formed by Cientis Technologies and the American College of Physicians to help physicians compare and implement electronic health records.

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With new $1.7M collaborative grant, U-M, Johns Hopkins researchers will develop dementia treatment tool for family caregivers – UofMHealth.org

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Aside from memory loss and cognitive impairments, often the most difficult aspect of caring for people with dementia is treating their disruptive changes in behavior.

With no reliable medications to treat them and limited information for caregivers regarding alternative therapies, these behavior changes are frequently the source of increased upset, stress and burden to families and often result in nursing home placement.

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A personal account of translating discoveries in an academic lab : Nature Biotechnology : Nature Publishing Group

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Robert Langer shares the experiences and lessons learned through his involvement with more than two dozen biotech startups.

I started my first company in 1987 because I realized it was an effective path for transforming science into life-saving and life-improving inventions. Startup companies provide one means for accomplishing ends that interested me: creating products that have a positive effect on human health. I did this first with a colleague (Box 1), but through the years I have also started many companies with students and postdocs in my MIT lab.

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